Institute of Environmental Science and Research
Browse
Developing allelic and stutter peak height models for a continuous method of DNA interpretation.pdf (1.37 MB)

Developing allelic and stutter peak height models for a continuous method of DNA interpretation.

Download (1.37 MB)
journal contribution
posted on 2019-12-09, 03:54 authored by Jo-Anne Bright, Duncan Taylor, James M. Curran, John S. Buckleton
Traditional forensic DNA interpretation methods are restricted as they are unable to deal completely with complex low level or mixed DNA profiles. This type of data has become more prevalent as DNA typing technologies become more sensitive. In addition they do not make full use of the information available in peak heights. Existing methods of
interpretation are often described as binary which describes the fact that the probability of the evidence is assigned as 0 or 1 (hence binary) (see for example [1] at 7.3.3). These methods are being replaced by more advanced interpretation methods such as continuous models. In this paper we describe a series of models that can be used to calculate
expected values for allele and stutter peak heights, and their ratio SR. This model could inform methods which implement a continuous method for the interpretation of DNA profiling data.

Funding

US National Institute of Justice - Grant No: 2011-DN-BX-K541

History

Usage metrics

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC