10.26091/ESRNZ.9730295.v1
Dengmiao Cheng
Dengmiao
Cheng
Yao Feng
Yao
Feng
Yuanwang Liu
Yuanwang
Liu
Jianming Xue
Jianming
Xue
Zhaojun Li
Zhaojun
Li
Dynamics of oxytetracycline, sulfamerazine, and ciprofloxacin and related antibiotic resistance genes during swine manure composting
Institute of Environmental Science and Research
2019
Veterinary Antibiotics
Oxytetracycline
Sulfamerazine
Ciprofloxacin
Swine manure composting
Antibiotic resistance genes
ARGs
China
Environmental Monitoring
Environmental Management
Genetic Immunology
Genetics
2019-08-28 04:13:28
Journal contribution
https://research.esr.cri.nz/articles/journal_contribution/Dynamics_of_oxytetracycline_sulfamerazine_and_ciprofloxacin_and_related_antibiotic_resistance_genes_during_swine_manure_composting/9730295
<p>Understanding the dynamics of veterinary antibiotic and
related antibiotic resistance genes (ARGs) during swine manure composting is
crucial in assessing the environmental risk of antibiotics, which could
effectively reduce their impact in natural environments. This study
investigated the dissipation of oxytetracycline (OTC), sulfamerazine (SM1) and
ciprofloxacin (CIP) as well as the behaviour of their corresponding ARGs during
swine manure composting. These antibiotics were added at two concentration
levels and two different methods of addition (single/mixture). The results
indicated that the removal efficiency of antibiotics by composting were ≥85%,
except for the single-SM1 treatment. The tetracycline resistance genes (TRGs)
encoding ribosomal protection proteins (RPP) and efflux pump (EFP) and
fluoroquinolone resistance genes (FRGs) could be effectively removed after 42
days. On the contrary, the TRGs encoding enzymatic inactivation (EI) and
sulfonamide resistance genes (SRGs) were enriched up to 31-fold (sul 2 in
single-low-SM1). Statistical analyses indicated that the behaviour of these
class antibiotics and ARGs were controlled by microbial activity and
significantly influenced by environmental factors (mainly C/N, moisture and pH)
throughout the composting process.</p>